A friend has been on anti-depression medication for the last two years, but now wants to try for a baby. Is it advisable for her to stay on the meds while trying to conceive?

Actually, I don't think this is an issue we can advise your friend on, because we're not healthcare professionals. If she goes off meds, there's a risk that her condition may go haywire which is very dangerous. If she continues on her meds, it may be too severe and cause fetal problems. Therefore, my suggestion is for your friend to consult a fertility specialist or inform the doctor she is seeing for her depression that she wishes to conceive. They will then find the best solution for her.