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As a normal part of pregnancy, your breathing may be affected by the increase in the hormone progesterone, which causes you to breathe in more deeply. ... Breathing may also become more difficult as your enlarging uterus takes up more space, resulting in pressure against your diaphragm (the muscle below your lungs). Seek emergency medical care if your shortness of breath is accompanied by chest pain, fainting, nausea, a bluish tinge to lips or nails, or a change in mental alertness — as these may be signs of a heart attack or pulmonary embolism.

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