My wife is highly against the idea of getting our daughter (and soon to be son) vaccinated! I completely disagree with her and think vaccinations are the right approach. How can I explain to my wife my point of view? What are your thoughts on the matter?

Allow her to explain her stance on the matter while keeping an open mind and truly listening to her. Acknowledge where she is coming from but also, if you feel strongly about it, emphasize th benefits of vaccination. Back your opinion up with data and don't speak out of emotion. Hope she'll come around!