Mild exposure to refrigerants is generally harmless. Poisoning is rare except in cases of abuse or exposure in a confined space. Symptoms of mild to moderate poisoning include: irritation of the eyes, ears, and throat headache nausea vomiting frostbite (liquid Freon) cough chemical burn to the skin dizziness Symptoms of severe poisoning include: fluid buildup or bleeding in the lungs burning sensation in the esophagus vomiting up blood decreased mental status difficult, labored breathing irregular heartbeat loss of consciousness seizures