Here's an article provided by a company that manufactures flanges for Medela, speCtra, and Ameda breastpumps. You can have a read to find out more on how to choose the sizes. http://maymom.com/index.php?option=com_content&view=article&id=78&Itemid=484 A lot of my friends had to trial and error. One of them mentioned that if you are using the Medela pump, you can go to their service centre (located at 81 Toh Guan Road East # 03-01 Secom Centre) and they could help you determine the appropriate size.
When purchasing flanges, it is all about a comfortable fit. It is an inexact science and apparently has nothing to do with the size of your breasts but rather the size of your nipples. Where do you intend to buy your flanges and/or breast pump from? Medela has a guide on choosing the appropriate size flange for different sized nipples. You can read about it here: http://www.medelabreastfeedingus.com/tips-and-solutions/13/choosing-your-personalfit-breastshield-size
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