Hi Gigi, thank you for your question! Your question was answered live on air with Dr Frans, who says:
There might be other reasons for being irritable, such as illness, or going on a holiday. It does depend on the environment that the baby is in right now. Your baby may be having an off day, and it may not be due to their internal brain changes.
We have tried our hardest to factor that into our research. It is important to realize that there are perhaps other factors as to why babies are being irritable.
You can view a recording of Dr Frans' Ask The Expert Session here: https://www.facebook.com/parenttown/videos/1258235770909093/
:)
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